Naltrexone/Bupropion: An Investigational Combination for Weight Loss and Maintenance

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Naltrexone/bupropion: an investigational combination for weight loss and maintenance.

Naltrexone/bupropion is an investigational combination for weight loss and maintenance in patients who are obese or have a BMI ≥ 27 kg/m(2) with comorbid diabetes, hypertension or hyperlipidemia. Pooled results from four phase 3 trials reveal placebo-subtracted mean weight loss of 4.7% (range 3.2-5.2%) with naltrexone/bupropion after 1 year (p < 0.001 vs. placebo in each trial). The placebo-sub...

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ژورنال

عنوان ژورنال: Obesity Facts

سال: 2011

ISSN: 1662-4033,1662-4025

DOI: 10.1159/000335352